Research Registry: Studies & Clinical Trials

In this research registry, we list ongoing studies and clinical trials. This gives patients with PMDD or PME a chance to learn about opportunities in which they may wish to participate. We offer this registry as a free service to allow scientists and patients to connect. All studies listed have Ethics Board Approval.

Information for Researchers:

Information for patients interested in participating in research studies:

Current Studies and Trials Recruiting Participants

Please note that IAPMD cannot answer any specific requests about the below studies. Please contact the researcher/establishment directly.

  • This is a research study by investigators at the University of Southern California examining alcohol use and the menstrual cycle. In this study, about half of participants will have Premenstrual Dysphoric Disorder (PMDD) symptoms, and the other half will not have PMDD symptoms.

    Participation will include answering surveys on your smart device, wearing a ring on your finger that measures your heart rate and skin temperature, and completing urine ovulation tests.

    Looking for: ages 21 and 40, live in California, drink alcohol, and have a regular menstrual cycle.

    See here for more information about the research study. Contact Nicole St. Denis with any questions or for further information.

    Click here to participate in the study.

  • This study seeks to understand how PMDD impacts cognitive processes, such as memory. It focuses on how emotional trauma might affect processes like thinking and learning.

    It includes completing an online cognitive test that takes approximately 20-30 minutes to complete.

    Looking for: ages 18 and over, biologically assigned female at birth (AFAB), currently experience a menstrual cycle and have not gone through the menopause, have a diagnosis or suspect PMDD/PMS, do not experience PMS/PMDD but have a normal menstrual cycle. The study is open to all gender identities and those taking medications like SSRIs to treat PMDD.

    Contact Dr. Sophie Hodgetts with any questions or for further information.

    Click here to participate in this study.

  • Researchers are studying relationships between hormone levels and mood symptoms across the menstrual cycle. Participation includes tracking your menstrual cycle, filling out questionnaires, and providing saliva and blood samples, plus three sessions conducted by telephone or video chat.

    Looking for: ages 18-50 years, based in Baltimore or the Washington D.C. area, and not use hormonal birth control or psychiatric medications.

    Compensation is provided.

    Apply here. Learn more here. For any queries, contact via here.

  • Researchers at Johns Hopkins University are seeking individuals to participate in a research study looking at views about psychedelics and the psychological effects of psychedelics. This specific survey focuses on individuals' emotions, beliefs, behaviors, and experiences related to using a drug, specifically in the context of premenstrual or perimenopausal symptoms.

    Looking for: Volunteers must be 18 years of age or older, have a menstrual cycle, and be willing to respond to an anonymous survey.

    Contact David Yaden with any questions or for further information.

    Click here to participate in this study.

  • Doctors are trying to learn more about the causes of and treatments for Premenstrual Dysphoric Disorder. Learn more and apply here. You are invited to call the National Institute of Mental Health at 301-496-9576 for information on our research studies on Premenstrual Dysphoric Disorder.

  • This study offer free diagnostic evaluation and, for those who qualify, free study-related treatment and/or monetary compensation. All studies are intended to investigate the causes of PMDD and will help guide the development of future treatment interventions.

    Learn more here. Take the 5-minute screener here.

Submitting your Research / Looking for Participants

We often get contacted by researchers looking for patients to take part in their research - and this is something we want to nurture and encourage! If you are a student/researcher and would like to submit your survey to appear on this page, please submit your details below. Please note that you must have evidence of Ethics Board approval to be considered to feature. To ensure high-quality data comes from your research it is vital that you are aware of the strict diagnostic criteria for PMDD. For researchers, we would recommend using The Carolina Premenstrual Assessment Scoring System (C-PASS) - an algorithm for making the DSM-5 diagnosis of Premenstrual Dysphoric Disorder (PMDD) using two cycles of daily symptom ratings on the Daily record of severity of problems (DRSP). The C-PASS diagnostic tool has recently been published in the American Journal of Psychiatry.

What to Consider When Applying to be a part of Research Trial / Study?

Although IAPMD does request that scientists have their research study methods reviewed and approved by appropriate regulatory bodies prior to posting on this registry, the safety and scientific validity of a study listed on IAPMD.org is the responsibility of the study sponsor and investigators. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating.

Those that have received funding from International Association for Premenstrual Disorders (IAPMD) are indicated with an asterisk (*).

Study information is provided by study sponsors and investigators, and they are responsible for ensuring that the studies follow all applicable laws and regulations. IAPMD does work hard to verify the scientific validity or relevance of the submitted information, however, study administrators should be contacted directly for further information and concerns.

Choosing to participate in a Clinical Study is an important personal decision. Before you participate in a study, discuss all options with your health care provider and other trusted advisers. For more information about participating in clinical studies, see Learn About Clinical Studies at clinicaltrials.gov, which includes questions that you might want to ask before deciding to participate in a study.

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What Is The Difference Between An Observational Study & A Clinical Trial?

Observational studies are, as the name suggests when people are observed in normal settings (i.e. Not trialing medications/treatments - just observing their symptoms/behaviors). Researchers may gather information, group volunteers, according to broad characteristics, and compare changes over time. These studies may help identify new possibilities for clinical trials. These studies may include surveys and focus groups and do not involve medical intervention - just observation of symptoms and effects of those symptoms.

Clinical trials are research studies performed in people that are aimed at evaluating a medical, surgical, or behavioral intervention. They are the primary way that researchers find out if a new treatment, like a new drug or diet, or medical device is safe and effective in people. Often a clinical trial is used to learn if a new treatment is more effective and/or has less harmful side effects than the standard treatment.

A clinical trial may also look at how to make life better for people living with a life-threatening disease or a chronic health problem.

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We make every effort to keep these trials listed up to date - if you notice any changes/additions that need to be made please do let us know by contacting us here.

For more information about using the information on iapmd.org, please also see Terms and Conditions. Please also see the IAPMD Medical Disclaimer for further information.