For many with PMDD, Premenstrual Dysphoric Disorder can already feel like a prison sentence. As hormones begin to rise and fall during the luteal phase of the ovulation cycle, those with PMDD begin to feel acute symptoms of irritability, anxiety, tension, depression, and (for some) hostility/aggression. So what happens when someone in a PMDD episode commits a punishable crime such as theft, assault, or even murder?